OSI-420 impurity - Names and Identifiers
OSI-420 impurity - Physico-chemical Properties
Molecular Formula | C21H21N3O4
|
Molar Mass | 379.41 |
Density | 1.30 |
Melting Point | 140-142°C |
Storage Condition | -20°C Freezer |
In vivo study | Desmethyl Erlotinib exhibits t 1/2 of 11.96±2.01 h in a pharmacokinetic study in Wistar rats. |
OSI-420 impurity - Introduction
OSI-420 Free Base is a compound with the chemical name 1-(4-amino-3-oxo-6-(4-(2-(6-(trifluoromethyl) aryl)) ethylamino) phenyl) hexahydro-2H-pyran-2-yl) ethanone. The following is an introduction to the nature, use, method and safety information of OSI-420 Free Base:
Nature:
-Appearance: White to light yellow solid.
-Melting point: About 110-116 ℃.
-Solubility: OSI-420 Free Base is soluble in organic solvents, such as ethanol, acetone and dichloromethane.
Use:
- OSI-420 Free Base is an anti-tumor drug used in cancer treatment research. It is a multi-targeted tyrosine kinase inhibitor and has anti-angiogenic and anti-tumor activities.
Preparation Method:
-The preparation of OSI-420 Free Base has not been publicly disclosed in the literature. In General, methods for preparing such compounds may involve organic synthesis and chemical reactions.
Safety Information:
- OSI420-Free Base is a laboratory synthetic drug, limited to research use.
-Standard laboratory safety practices and personal protective measures should be followed for the use and handling of OSI-420 Free Base.
-specific safety information, such as toxicity, corrosivity and environmental impact needs to be referred to the safety data form (SDS) provided by the chemical supplier.
Last Update:2024-04-09 20:02:46